Table of Contents
Can Depakote make you manic?
The symptoms vary widely in their pattern, severity, and frequency. Some people may alternate between extreme episodes of mania and depression. Antiepileptic drugs, including Depakote may cause suicidal thoughts or actions in a small number of people, about 1 in 500.
Is 1500 mg of Depakote too much?
Depakote tablets are administered orally. The recommended starting dose is 250 mg twice daily. Some patients may benefit from doses up to 1,000 mg/day. In the clinical trials, there was no evidence that higher doses led to greater efficacy.
What happens when Depakote levels are too high?
Unusual weight gain or loss. Tremors. Blurred or double vision, uncontrolled eye movements. Mood swings.
Can bipolar suddenly worsen?
When it’s diagnosed as something else, symptoms of bipolar disorder can get worse. This usually occurs because the wrong treatment is provided. Other factors of a misdiagnosis are inconsistency in the timeline of episodes and behavior. Most people don’t seek treatment until they experience a depressive episode.
How quickly does Depakote work for mania?
Tablets take 4 hours to reach a peak, Depakote sprinkles take just over three. Food can delay the absorption of Depakote (food has a more significant effect on the tablets compared with the sprinkles). It may take several weeks of regular dosing before an effect on mood or seizure frequency is reported.
What is acute mania in bipolar disorder?
Identified as extended periods of elevated, expansive, or irritable mood. Depression. Usually seen by periods of sad hopelessness.
How quickly does Depakote work for bipolar?
What are signs of Depakote toxicity?
Key signs and symptoms include: CNS depression, lethargy and encephalopathy, respiratory depression, nausea/vomiting and myoclonus. Laboratory abnormalities are particularly helpful in this case.
What level of Depakote is toxic?
The therapeutic range for valproic acid is 50-100 mcg/mL. The toxic level is >100 mcg/mL.