How do dengue serotypes differ?

Human Immunology 69(2): 122–128. 9. Vaughn DW, Green S, Kalayanarooj S, Innis BL, Nimmannitya S, et al. (2000) Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity.

Which serotype of dengue is most common?

Dengue virus 3 (DENV-3) was the most common serotype found (68.3\%), followed by DENV-2 (19.5\%) and DENV-1 (4.9\%).

How do serotypes differ?

The O antigens are distinguished by their different chemical make-up. The H antigens are distinguished by the protein content of the flagella. Each O and H antigen has a unique code number. Scientists determine the serotype based on the distinct combination of O and H antigens.

What are the four different strains of dengue fever?

There are four serotypes of dengue viruses, designated as DENV-1, DENV-2, DENV-3, and DENV-4; all are transmitted from human to human through the bite of certain species of Aedes mosquitoes, primarily Ae. aegypti and Ae.

What is serotype 2 dengue?

Dengue serotype 2 (DEN-2) viruses with the potential to cause dengue hemorrhagic fever have been shown to belong to the Southeast (SE) Asian genotype. These viruses appear to be rapidly displacing the American genotype of DEN-2 in the Western Hemisphere.

How is dengue serotype determined?

The viral RNA genome-based reverse-transcription PCR (RT-PCR) is the most widely used method to identify DENV serotypes in patient specimens. However, the non-structural protein 1 (NS1) antigen as a biomarker for DENV serotyping is an emerging alternative method.

What is stage1 dengue?

Stage I:Acute fever stage.(~Day 1-5). At this phase the patients have high fever (39-40 degree Celsius) with aching, abdominal pain, nausea, vomiting. Anti-pyritic such as paracetamol is important to lower body temperature in order to provide the body minimizes fluid loss.

Which dengue serotype is prevalent in India?

Dengue virus serotypes were tested in 4963 samples collected across India in 2018. DENV-2 was the most prevalent serotype in many states of India. Two genotypes of DENV-1 (I and V) were circulating. Two lineages of DENV-2 genotype IV were circulating.

What is a viral serotype?

A serotype or serovar is a distinct variation within a species of bacteria or virus or among immune cells of different individuals. These microorganisms, viruses, or cells are classified together based on their surface antigens, allowing the epidemiologic classification of organisms to the subspecies level.

How are serotypes detected?

What is Stage 3 dengue?

Stage III: This is the recovery phase. It usually takes a few days for the patients to get back to normal. At this stage, the patient gains back its appetite, has a slower pulse rate, has a convalescent rash at legs and arms.

Can you get dengue twice?

A patient can get dengue from two or more different strains of dengue. Hence a patient can suffer from dengue more than once. When Dengue Strikes Twice: When patients are infected with the dengue virus they can come down with dengue hemorrhagic fever and suffer massive internal bleeding and liver damage.