How many people gain weight on olanzapine?

In a study of people early in the course of schizophrenia, who received treatment for up to one year, approximately eight out of ten people prescribed olanzapine developed significant weight gain (defined as an increase of 7\% or more of their starting weight).

Can you avoid weight gain on olanzapine?

In this study, we found that co-treatment with betahistine is effective in significantly reducing weight gain induced by olanzapine through the chronic treatment course.

How do I reverse the weight gain from Zyprexa?

If Zyprexa causes significant weight gain, for example, switching to Geodon may deliver similar benefits with little or no risk of causing weight gain. Try a different form of the same medication. Olanzapine (Zyprexa), for example, is also offered as a dissolvable tablet (Zydis) that melts in your mouth.

Will I lose weight if I stop taking olanzapine?

People who stop taking antipsychotics usually see gradual weight loss. Stopping a medication, however, is not always possible, and it can sometimes have serious repercussions. A person should never stop taking a prescribed medication without speaking to a doctor about it first.

How quickly do you gain weight on olanzapine?

We also found that 70.8\% patients increased their appetite within the first 4 weeks of initial olanzapine treatment with a mean of 20.3 days to increase. Some patients even increased their appetite as early as the third day after olanzapine treatment.

Will I gain weight on 2.5 mg olanzapine?

Very common: Weight gain13 , elevated triglyceride levels14 , increased appetite. Common: Elevated cholesterol levels15 . Very common: Sedation (including: hypersomnia, lethargy, somnolence).

Does 2.5mg olanzapine cause weight gain?

This drug may also cause significant weight gain and a rise in your blood cholesterol (or triglyceride) levels, especially in teenagers. These effects, along with diabetes, may increase your risk for developing heart disease. Discuss the risks and benefits of treatment with your doctor.

What can I take instead of olanzapine?

Types of interventions

• Olanzapine: any oral form of application, any dose.
• Other atypical antipsychotic drugs: amisulpride, aripiprazole, clozapine, quetiapine, risperidone, sertindole, ziprasidone, zotepine: any oral form of application, any dose.

What is an alternative medication to olanzapine?

Healthcare providers may recommend Zyprexa substitutes such as therapy or other antipsychotic medications, such as Haldol (haloperidol), Clozaril (clozapine), and others. The FDA has licensed Zyprexa, (generic name olanzapine) for the treatment of schizophrenia and mania or depressive episodes with bipolar disorder.

Does olanzapine change metabolism?

Indeed, reduced body temperature after olanzapine treatment may generate many of the known side effects of this antipsychotic drug. The authors’ new findings also demonstrate that olanzapine alters peripheral glucose metabolism, which may contribute to impaired insulin sensitivity.

Does 2.5 mg of olanzapine cause weight gain?

Which antipsychotic has the least weight gain?

Antipsychotics with a lower risk of weight gain are:

• Aripiprazole (Abilify)
• Asenapine (Saphris)
• Brexipiprazole (Rexulti)
• Haloperidol (Haldol)
• Lurasidone (Latuda)
• Ziprasidone (Geodon)

Does olanzapine cause increased appetite?

Zyprexa increases body weight through several mechanisms. One such is increased appetite. Most patients who take Zyprexa complain of increased appetite. According to clinical trials, it is independent to the effect seen following the cure of psychosis (Psychosis/schizophrenia/depression known to cause loss of appetite).

Does olanzapine cause diabetes?

Olanzapine can cause an increase in blood sugar levels and can increase the risk of developing diabetes. Tell your healthcare provider if you develop signs of diabetes while taking olanzapine. Signs of diabetes can include increased thirst, increased urination, and hunger.

Does Zyprexa Zydis cause weight gain?

A: Weight gain is a common side effect of Zyprexa (olanzapine). According to the prescribing information for Zyprexa, 57\% of patients in clinical trials reported weight gain of up to 5 pounds, 15\% reported weight gain of 5-10 pounds, and 2\% reported weight gain of 10-15 pounds.

Which antipsychotics are least likely to cause weight gain?

Atypical Antipsychotics with the Lowest Risk of Weight Gain. Clozapine and olanzapine convey the greatest risk for abnormalities in these indices; risperidone and quetiapine convey moderate risk, and aripiprazole and ziprasidone are the least likely to affect metabolic indices. Newly approved lurasidone also has a mild side-effects profile.