Table of Contents
- 1 Which amino acid is most likely to be located in the interior of a globular protein?
- 2 What distribution of amino acids would you expect to find in a protein embedded in a lipid bilayer?
- 3 What amino acids is most likely to be found on the outside of a properly folded protein in the cytoplasm?
- 4 Where would serine be found in a globular protein?
- 5 Is serine hydrophobic or hydrophilic?
- 6 Which amino acids would you expect to find in the transmembrane region of the protein?
- 7 Where does amino acid synthesis occur in the cell?
- 8 Which amino acids would be found on the outside of the protein?
- 9 What amino acids are found in serine?
- 10 What amino acids have a hydrophobic side chain?
- 11 What are the side chains of proteins made of?
Which amino acid is most likely to be located in the interior of a globular protein?
hydrophobic amino acid side
Most often, the hydrophobic amino acid side chains are buried, closely packed, in the interior of a globular protein, out of contact with water. Hydrophilic amino acid side chains lie on the surface of the globular proteins exposed to the water.
What distribution of amino acids would you expect to find in a protein embedded in a lipid bilayer?
Explanation: The middle of the phospholipid bilayer is composed of nonpolar fatty acid tails. As a result, we would expect to find a nonpolar amino acid in the middle of the bilayer as part of the integral protein. Leucine is a nonpolar amino acid, so it could be found in the middle.
Where are amino acids made into protein?
ribosome
To build proteins, cells use a complex assembly of molecules called a ribosome. The ribosome assembles amino acids into the proper order and links them together via peptide bonds. This process, known as translation, creates a long string of amino acids called a polypeptide chain.
What amino acids is most likely to be found on the outside of a properly folded protein in the cytoplasm?
Proteins that are in aqueous environments, such as the cytoplasm of the cell, have their amino acids arranged so that those with hydrophilic side chains (such as threonine or lysine) predominate on the exterior of the protein so as to interact with water.
Where would serine be found in a globular protein?
interior
Serine would be in the interior, and alanine would be on the exterior of the globular protein.
Which amino acid would most likely be found in the interior of a water-soluble protein?
Which of the following series of amino acids is most likely to be buried in the center of a water-soluble globular protein? YES, THIS IS THE MOST LIKELY SEQUENCE. Ala, Leu and Phe all have nonpolar side chains and so this series is highly likely to be buried in the hydrophobic core of a water-soluble globular protein.
Is serine hydrophobic or hydrophilic?
‘Polarity’
| Amino acid | Abbreviations | IMGT classes of the amino acids side chain properties [1] |
|---|---|---|
| Methionine | Met | hydrophobic (1) |
| Phenylalanine | Phe | hydrophobic (1) |
| Proline | Pro | neutral (2) |
| Serine | Ser | neutral (2) |
Which amino acids would you expect to find in the transmembrane region of the protein?
The amino acids most likely to occur in the transmembrane domain of integral membrane proteins are the hydrophobic Amino acids.
How are amino acids incorporated into protein?
In the natural protein translation process, an amino acid is first charged onto a transfer RNA (tRNA) by an aminoacyl-tRNA synthetase (aaRS) using a specific anti-codon. Then, the amino acid–charged tRNA is delivered by the elongation factor Tu (EF-Tu) to the ribosome, where translation occurs.
Where does amino acid synthesis occur in the cell?
Synthesis of arginine is carried out in cytoplasm. However, the precursors required for this process originate in mitochondria by the degradation of three other amino acids, that is, glutamine, glutamate, and proline (Figure 4).
Which amino acids would be found on the outside of the protein?
Six amino acids have side chains that are polar but not charged. These are serine (Ser), threonine (Thr), cysteine (Cys), asparagine (Asn), glutamine (Gln), and tyrosine (Tyr). These amino acids are usually found at the surface of proteins, as discussed in the Proteins 2 module.
Which amino acid is most likely to be found within the cell membrane?
The interior of the phospholipid bilayer is a hydrophobic environment; therefore, leucine and other hydrophobic amino acids are more commonly found in the membrane-spanning portions of transmembrane proteins.
What amino acids are found in serine?
These are serine (Ser), threonine (Thr), cysteine (Cys), asparagine (Asn), glutamine (Gln), and tyrosine (Tyr). These amino acids are usually found at the surface of proteins, as discussed in the Proteins 2 module. Shown at the right is the structure of serine.
What amino acids have a hydrophobic side chain?
The nine amino acids that have hydrophobic side chains are glycine (Gly), alanine (Ala), valine (Val), leucine (Leu), isoleucine (Ile), proline (Pro), phenylalanine (Phe), methionine (Met), and tryptophan (Trp). Shown at the right is the structure of valine.
Why amino acids and proteins are the building blocks of life?
Amino acids and proteins are the building blocks of life. The human body uses amino acids to make proteins to help the body:
What are the side chains of proteins made of?
These side chains are composed mostly of carbon and hydrogen, have very small dipole moments, and tend to be repelled from water. This fact has important implications for proteins’ tertiary structure (see the Proteins 2 module for a discussion of tertiary structure). Six amino acids have side chains that are polar but not charged.