Why is the concentration of glucose in the hepatic portal vein higher than the hepatic vein?

Ingestion of glucose or infusion of glucose into the portal vein creates a negative arterial-portal glucose gradient (portal vein concentration higher than that in the artery) that is sensed within the liver, giving rise to the portal glucose signal, which is associated with an increase in net hepatic glucose uptake ( …

Is glucose high in hepatic portal vein?

Parallel to the changes in food intake, hepatic glycogen content was increased by glucose infused into the hepatic portal vein but not jugular vein. Conversely, systemic plasma glucose levels were increased by glucose infused into the jugular vein but not hepatic portal vein.

What is the difference between the hepatic portal vein and the hepatic vein?

Hepatic portal vein carries blood and nutrients from the stomach, spleen, intestines and gall bladder to the liver. The hepatic vein carries deoxygenated blood from the liver back to the right atrium of the heart via the inferior vena cava.

Which blood vessel has the highest concentration of glucose?

hepatic portal veins
Shortly after a meal, the hepatic portal veins have the highest blood glucose levels before sugar is post-hepatically diffused in the systemic circulation. Thus, immediately after a meal, it is the hepatic portal vein that produces the highest amino acid and glucose concentration.

Why does the liver have a hepatic portal vein and an hepatic vein?

The liver has a dual blood supply. The portal vein (which is rich in nutrients and relatively high in oxygen) provides two thirds of blood flow to the liver. The hepatic artery (which is oxygen-rich) supplies the rest. The hepatic veins drain the liver into the inferior vena cava.

Why hepatic vein contains more urea?

Option B Hepatic vein: The hepatic veins carry deoxygenated blood from the liver to the inferior vena cava. The hepatic vein is rich in urea. This is because urea is a by-product of amino acid catabolism, which occurs in the liver.

What is hepatic glucose?

Net hepatic glucose production is the summation of glucose fluxes from gluconeogenesis, glycogenolysis, glycogen synthesis, glycolysis and other pathways.

Why does the liver have a hepatic portal vein and hepatic vein?

Why does the liver have both a hepatic artery and a hepatic portal vein as a blood supply?

The liver is connected to two large blood vessels, the hepatic artery and the portal vein. The hepatic artery carries blood from the aorta to the liver, whereas the portal vein carries blood containing the digested nutrients from the entire gastrointestinal tract, and also from the spleen and pancreas to the liver.

Why does the hepatic portal vein have more glucose after eating?

All cells of the body require glucose for cellular respiration to make energy. The liver receives blood from the small intestines through the hepatic portal vein. After a large meal, the hepatic vein would transport glucose rich blood from the small intestines to the liver.

What is the importance of hepatic portal vein?

The hepatic portal vein supplies the liver with metabolic substrate and it ensures that substances ingested are first processed by the liver before reaching the systemic circulation. In this process ingested toxins can be detoxified by the hepatocytes before they are released in the systemic circulation.

Why is the hepatic portal vein deoxygenated?

The first is the hepatic artery which delivers oxygenated blood from the general circulation. The second is the hepatic portal vein delivering deoxygenated blood from the small intestine containing nutrients. The blood flows through the liver tissue to the hepatic cells where many metabolic functions take place.

How does the hepatic portal vein increase blood glucose?

Firstly, blood glucose in the hepatic portal vein increases after a meal and this is due to the hepatic portal vein transporting blood from the gut to the Liver. Therefore, blood glucose will increase as food is digested and glucose absorbed by the gut.

What is the difference between hepatic vein and hepatic portal vein?

In a healthy person the blood glucose level in the hepatic vein fluctuates much less than that in the hepatic portal vein. Explain why. Firstly, blood glucose in the hepatic portal vein increases after a meal and this is due to the hepatic portal vein transporting blood from the gut to the Liver.

What happens during the postabsorptive phase of the glucose cycle?

During the postabsorptive phase, the liver releases stored glucose into circulation, so there is more glucose coming out of the liver via the hepatic veins than there is going into it via the hepatic portal vein.

What happens when glucose levels are too low in the liver?

If at any point, the blood glucose are too low, these glycogen molecules are broken down in the Liver back to glucose in a process known as glycogenolysis. The hepatic vein is responsible for transporting deoxygenated blood from the Liver back into the circulation after it has been filtered by the Liver. Answered by Lucinda G. • Biology tutor